Toni is furious to discover that Todd failed to deliver a message from a remorseful Greg before the wedding. Claiming that she needs closure but actually hoping to rub her happiness in Greg's face, she insists that she needs to meet with him. Todd fears that Toni still has feelings for Greg and threatens to leave her if she sees him. Toni declares that Todd needs to trust her; she ignores his ultimatum and meets with Greg anyway. Meanwhile, Joan is devastated when William's nephew/son cries every time she holds him, as she sees it a a sign that she wouldn't be a good mother. After Jabari tells Maya and Lynn that his classmates think they are lesbians, Maya angers Lynn by saying that she wouldn't even be her type.
Staff critiques vex Jack, who demands honesty and gets it, especially from servile Finch; a role reversal with Nina makes Maya a partygoer.
Matt and Sarah begin their student rotation in the ER, but get off to a bad start by arriving late and angering Dr. Norton, the attending ER physician. Matt and Sarah's relationship is tested when Matt quickly demonstrates an aptitude for the work, but Sarah accuses him of trying to make himself look better than the other students, especially her. However, Matt ends up looking foolish when he can't figure out how to turn off the ringer on his cell phone and he gets stuck fielding calls from his family. Matt's day ends tragically, leaving him to question his destiny.
Tired of all the bounty hunters and robots failing, Aku fights Jack, mano y mano.
Robert and Amy convince their families to spend Thanksgiving together. When the Barones arrive at the Pennsylvania home of Amy's parents, they find that their differing family traditions encourage lots of lively conversation.
Jimmy injuring his back making out with Christine throws a wrench into Don's plans to take him on a father-son ice-fishing tournament.
Stitch has been recently very successful at capturing and repurposing the Experiments, but it's gone to his head. He thinks he's too good for everything and is being a royal pain. But things are set to change when Pleakley goes into Jumba's ship and sees an experiment pod with the number '627' on it. Jumba has been making a new experiment. Luckily, it's in containment. That is, until they leave the ship and it escapes! Now it's employed by Gantu and Stitch wants to prove he's better than it. But he just gets beaten, and as 627 can't be turned good, Lilo and Stitch are in trouble...
When Nikki becomes Professor Oglevee's teaching assistant, she butts heads with the pretty young student who flirts with him for special treatment. Meanwhile, Kim, Stevie, T, Regina and Freddy compete for $5,000 by volunteering for a psych study in which they are forced to live for three days in cramped quarters.
The day-to-day lives of three orphaned children who are adopted by aliens that have trouble adjusting to the local culture.
In jail after his escapade at Ellen's party, Geoffrey is visited by the ghost of his dead mentor Oliver, who cousels him on the danger of trying to ignore his past feelings for Ellen, the woman who once broke his heart. Meanwhile, Holly and Richard work on their merchandising scheme, which involves a Shakespeare themed village of retail stores. Geoffrey is finally forced to fire Darren as director, to the relief of the cast but the worry of the Board of Directors.
Realizing he's losing someone special, Charlie plans a Thanksgiving dinner to convince her he's a family guy and that she should be with him.
When Sydney is taken into custody by the NSC, Jack and Vaughn have no choice but to ally themselves with Sloane to rescue her. But with only hours to spare before she is forced to undergo a radical surgery to recover her memories, they must put togther an extraction team, headed by freelance operative Brill (Richard Roundtree, "Shaft"). Meanwhile, Lauren faces an impossible choice -- side with the NSC, who she wants to believe is doing the right thing, or with her husband.
Bianca, a woman from the future, arrives to take Chris's powers, and Leo learns that she is actually part of an assassin family of witches. Meanwhile, Paige decides to move in with Richard, while Phoebe ponders joining Jason in Hong Kong.
Gob decides to lock himself in his father's prison for 24 hours to get back in with the alliance, and to spend quality time with his father. Michael takes Gob's girlfriend to an awards show, and Buster inadvertently flirts with his mother's rival.
After making over $3000 from his own museum featuring a $1000 bill, Bart takes the family to London (on the suggestion of Grampa), where Homer is arrested for treason after crashing into the Queen.
Malcolm skips out on Thanksgiving to go to a party; Reese becomes abusive to Hal and Dewey as he attempts to prepare Thanksgiving dinner.
The bludgeoning of a rich family patriarch has the detectives investigating several suspects, each with their own motives: his estranged wife whom he was about to divorce, a male friend of hers who was a parolee, their childrens' nanny, the victim's brother in law who is a doctor, even the oldest son. Goren and Carver call the family of suspects together to sort it all out... in family court.
Alan Shore uses questionable, if not illegal, tactics in representing his clients — Ted Grayson, a mentally unstable man accused of murder, and Karen Evanson, a woman who claims her husband's suicide was induced by a prescription drug.